Clinical implications of postsurgical adhesions
نویسندگان
چکیده
منابع مشابه
Epidemiology and Prevention of Postsurgical Adhesions Revisited.
OBJECTIVE To provide a comprehensive review of recent epidemiologic data on the burden of adhesion-related complications and adhesion prevention. Second, we elaborate on economic considerations for the application of antiadhesion barriers. BACKGROUND Because the landmark SCAR studies elucidated the impact of adhesions on readmissions for long-term complications of abdominal surgery, adhesions...
متن کاملFibrin-targeted block copolymers for the prevention of postsurgical adhesions.
Despite advances in surgical methods, postsurgical adhesions (PSA) remain a significant clinical challenge affecting millions of patients each year. These permanent fibrous connections between tissues result from the bridging of wounded internal surfaces by an extended fibrin gel matrix (FGM). Adhesion formation is a result of a systems level convergence of wound healing pathways, complicating ...
متن کاملDrug-loaded electrospun nanofibrous sheets as barriers against postsurgical adhesions in mice model
Objectives: Postsurgical adhesion is one of the common complications after surgery. Some anti-adhesion barriers are commercially available which are not customary used by physicians as much as expected because of ineffectiveness. Recently, nanofibers have been introduced as anti-adhesion barriers with t...
متن کاملInvolvement of the Ubiquitin-Proteasome System in the Formation of Experimental Postsurgical Peritoneal Adhesions
We investigated the Ubiquitin-Proteasome System (UPS), major nonlysosomal intracellular protein degradation system, in the genesis of experimental postsurgical peritoneal adhesions. We assayed the levels of UPS within the adhered tissue along with the development of peritoneal adhesions and used the specific UPS inhibitor bortezomib in order to assess the effect of the UPS blockade on the perit...
متن کاملdrug-loaded electrospun nanofibrous sheets as barriers against postsurgical adhesions in mice model
objectives: postsurgical adhesion is one of the common complications after surgery. some anti-adhesion barriers are commercially available which are not customary used by physicians as much as expected because of ineffectiveness. recently, nanofibers have been introduced as anti-adhesion barriers with the potential of drug delivery. in the light of role of inflammation and oxidative stress in a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Human Reproduction Update
سال: 2001
ISSN: 1355-4786,1460-2369
DOI: 10.1093/humupd/7.6.567